This is the year the world came onchain.
When we launched our first State of Crypto report, the industry was still in its adolescence. The total crypto market was worth about half what it is today. Blockchains were much slower, more expensive, and le
Each year, the State of Crypto report from a16z crypto cuts through the noise and tracks crypto’s evolution across markets, technology, policy, and culture.
Now in its fourth edition, the 2025 State of Crypto report reveals how crypto has gone ma
Matt Kaeberlein (CEO at Optispan, Inc.) is an affiliate professor of Oral Health Sciences at the University of Washington, and co-director of the Dog Aging Project. Dr. Kaeberlein’s research interests are focused on understanding biological mechanisms of aging in order to facilitate translational interventions. He is also a Fellow of the American Association for the Advancement of Science (AAAS), the American Aging Association (AGE), and the Gerontological Society of America (GSA).
In this presentation at our second annual a16z crypto Founders Summit — where we gather top leaders in crypto for a few days of connection, inspiration and fun covering art, engineering, building in web3, and much more — Kaeberlein shared findings from research on understanding biological mechanisms of aging. See also the below video for a conversation with Kaeberlein that followed this presentation (with a16z crypto’s Guy Wuollet), on promoting healthspan and improving quality of life for people and companion animals: • On promoting healthspan and quality o…